LD50

Half-die measurement

LD50 is a toxicology measurement: the dose of a substance lethal to 50 percent of a test population, typically lab animals.

It quantifies how poisonous something is—a lower LD50 means greater toxicity: Botulinum toxin has an extremely low LD50.

The metric helps compare dangers across substances but has limitations for predicting human outcomes.

substances

pesticide

Agent destroying harmful organisms

pharmaceutical · chemical · poison · cyanide · arsenic · strychnine · botulinum · ricin · paraquat · carcinogen

toxicology

toxicity

Capacity to cause harm

potency · sublethal · toxicant · pharmacokinetics · bioavailability

testing

rodent

Gnawing mammal order

  • mouseSmall gnawing mammal
  • ratRodent or informer
  • oralOf the mouth

dermal · inhalation · injection · extrapolation · mortality

safety

tolerance

Willingness to accept difference

precaution

Opposites
LETHALITY vs SAFETY THRESHOLD

LD50safe dose

Amount causing no harm

therapeutic dose · margin of safety · safety margin · recommended dose

Family

lethal, lethality, lethally, dose, doses, dosage, dosages, dosed, dosing

Familiarity
Top 1,000,000
Profile
Used worldwide · Timeless · Abstract · Negative · Rated PG