solubilization

Rendering something soluble

Solubilization is the process of making something soluble—able to dissolve in a liquid.

The term appears most often in chemistry, biochemistry, and pharmacology, where researchers solubilize compounds to study them or deliver them effectively: The drug required solubilization before it could be absorbed.

The process may involve adding surfactants, adjusting pH, or using specialized solvents.

dissolution

dissolve

Disperse into liquid

hydration · miscible · precipitate · supersaturation · solvation · wetting · rate-limiting · intrinsic · thermodynamic · kinetic

chemistry

solute

Substance absorbed by solvent

lipophilic · polarity · miscibility · aqueous · organic · intermolecular · partitioning · chelation · surfactant · micelle

emulsification

emulsifier

Combines immiscible liquids

stabilizer · homogenization · interface · coalescence · microemulsion · phospholipid · cream · lotion · dispersion

pharmaceutical

bioavailability

Fraction reaching active circulation

absorption · permeability · tablet · capsule · suspension · nanoparticle · amorphous · crystalline · API · dosage

techniques

sonication

Sound-based particle agitation

milling · spray-drying · extrusion · high-pressure · reflux · digestion

Opposites
phase transition direction

solubilizationprecipitation

Atmospheric water deposit

crystallization · flocculation · coagulation · sedimentation · deposition

molecular dispersion state

solubilizationaggregation

Combined collection of items

agglomeration · coalescence · clumping

Family

solution, resolute, soluble, insoluble, solubility, dissolvable, insolubility, solubilized, insolubly

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