neuromodulator

Neural signal modifier

A neuromodulator is a chemical substance that alters how neurons communicate, typically by adjusting the strength or duration of signals rather than directly triggering them.

Unlike neurotransmitters that act quickly at specific synapses, neuromodulators like dopamine, serotonin, and norepinephrine diffuse more broadly and influence mood, arousal, and attention.

Caffeine affects neuromodulators that regulate sleep.

biochemical

dopamine

Reward-linked neural messenger

GABA · glutamate · endorphins · oxytocin · vasopressin · histamine · adenosine · substance P · neuropeptide · nitric oxide

neural

synapse

Nerve signal crossing point

signal · axon · dendrite · potentiation · inhibition · excitation · presynaptic · reuptake · binding · release

cognitive

mood

Prevailing emotional condition

reward · sleep · appetite · pain · memory · learning · emotion · stress response · wakefulness · pleasure

pharmacological

agonist

Receptor-binding trigger molecule

anxiolytic · analgesic · SSRI · SNRI · dose-response · therapeutic · side effects · tolerance · dependence · pharmaceutical

clinical

depression

Prolonged low state

addiction · ADHD · bipolar · insomnia · chronic pain · fibromyalgia · migraine · autism · OCD · PTSD

Opposites
signaling mechanism

neuromodulatorneurotransmitter

Synaptic chemical messenger

glutamate · GABA · acetylcholine

neural effect direction

neuromodulatorneurotoxin

Poison attacking neural tissue

Family

neuromodulation, neuromodulators

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