disease-modifying
Changes illness course
Disease-modifying describes treatments that alter the underlying course of a disease rather than merely relieving symptoms.
The term appears most often in contexts like multiple sclerosis, rheumatoid arthritis, and Alzheimer's disease, where disease-modifying therapies aim to slow progression or prevent damage: The new drug is the first disease-modifying treatment approved for early-stage Alzheimer's.
Medication combating joint inflammation
- biologicLiving-organism-derived drug
- methotrexateAntifolate chemotherapy agent
- hydroxychloroquineAntimalarial and immunosuppressant drug
- immunosuppressantAgent reducing bodily defenses
Ability to produce results
- trialJudicial examination of claims
- indicationSign of what's coming
- first-lineTried before alternatives
- second-lineBackup or alternative approach
monotherapy · long-term · outcome · side-effect · monitoring · dosing · subcutaneous · intravenous
How disease develops
- progressionSequential forward movement
- inflammationProtective tissue response
- autoimmuneBody attacks itself
- cytokineImmune signaling molecule
T-cell · B-cell · antibody · receptor · signaling · cascade · pathway · neurodegeneration
Chronic autoimmune disorder
- AlzheimersProgressive memory-destroying brain disease
- ParkinsonsDegenerative brain condition
- ALSMotor neuron disease
- osteoarthritisCartilage breakdown in joints
vasculitis · scleroderma · chronic · degenerative · neurological · progressive
antirheumatic
Medication combating joint inflammation
- biologicLiving-organism-derived drug
- methotrexateAntifolate chemotherapy agent
- hydroxychloroquineAntimalarial and immunosuppressant drug
efficacy
Ability to produce results
- trialJudicial examination of claims
- indicationSign of what's coming
- first-lineTried before alternatives
second-line · monotherapy · long-term · outcome · side-effect · monitoring · dosing · subcutaneous · intravenous · oral
pathogenesis
How disease develops
- progressionSequential forward movement
- inflammationProtective tissue response
- autoimmuneBody attacks itself
cytokine · T-cell · B-cell · antibody · receptor · signaling · cascade · pathway · neurodegeneration · demyelination
lupus
Chronic autoimmune disorder
- AlzheimersProgressive memory-destroying brain disease
- ParkinsonsDegenerative brain condition
- ALSMotor neuron disease
osteoarthritis · vasculitis · scleroderma · chronic · degenerative · neurological · progressive
disease-modifyingsymptomatic
Showing signs of disease
palliative · analgesic · antipyretic · pain-relieving · anti-inflammatory
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