extrinsic pathway
External coagulation route
The extrinsic pathway is one of two cascades that trigger blood clotting, activated when tissue damage exposes blood to tissue factor outside the blood vessels.
It's called extrinsic because the trigger comes from outside the bloodstream, unlike the intrinsic pathway, which responds to factors within the blood itself.
Both pathways converge to form a clot.
- coagulationLiquid solidifying into mass
- clottingBlood solidifying process
- blood clotCoagulated mass in vessels
- cascadeSuccessive downward flow
- bloodBody's oxygen carrier
hemostasis · fibrin · thrombin · platelets · wound · injury · tissue damage · bleeding · prothrombin · trauma · vascular · membrane · phospholipid · activation · proteases · serine · intrinsic · hemorrhage
- blood clottingfibrin, thrombin, prothrombin, fibrinogen, platelet
- Cell Deathapoptosis, necrosis, ferroptosis, Bcl-2, Bad
extrinsic, extrinsically, pathway, path, pathways, extra, exterior, external, externally