cachexia
Disease-caused muscle loss
Cachexia is a severe wasting syndrome characterized by extreme weight loss, muscle atrophy, and weakness that cannot be reversed by simply eating more.
It typically accompanies serious chronic illnesses such as cancer, AIDS, heart failure, or kidney disease.
Unlike ordinary malnutrition, cachexia involves metabolic changes that cause the body to break down its own tissue.
The cancer patient's cachexia left him too weak to walk.
Extreme bodily thinness
- muscle wastingLoss of tissue mass
- atrophyWasting from disuse
- catabolismMetabolic molecular dismantling
- consumptionUsing up of resources
deterioration · body composition · wasting syndrome · withering · shrinkage · depletion
Weariness from prolonged exertion
- weaknessDeficiency in force
- anorexiaEating disorder, self-starvation
- weight lossReduction in body mass
- pallorUnhealthy facial whiteness
frailty · exhaustion · lethargy · debility · lassitude · malaise · asthenia · loss of appetite
Disease from dietary inadequacy
- undernourishmentInsufficient dietary intake
- malabsorptionFailed intestinal nutrient uptake
- nutritional supportAid ensuring adequate nourishment
- caloric deficitIntake below expenditure
protein deficiency · refeeding · supplementation · inanition
Uncontrolled cell proliferation disease
- AIDSImmune deficiency syndrome
- tuberculosisMycobacterial lung disease
- COPDChronic obstructive pulmonary disease
- heart failureInadequate blood pumping condition
chronic disease · renal failure · sepsis · rheumatoid arthritis · Crohn's disease · cirrhosis · malignancy · inflammatory disease
Immune signaling proteins
- inflammationProtective tissue response
- hypermetabolismAbnormally elevated metabolic rate
- proteolysisEnzymatic protein breakdown
- lipolysisMetabolic fat decomposition
interleukin · insulin resistance · energy expenditure · hormonal imbalance
emaciation
Extreme bodily thinness
- muscle wastingLoss of tissue mass
- atrophyWasting from disuse
- catabolismMetabolic molecular dismantling
consumption · deterioration · body composition · wasting syndrome · withering · shrinkage · depletion
fatigue
Weariness from prolonged exertion
- weaknessDeficiency in force
- anorexiaEating disorder, self-starvation
- weight lossReduction in body mass
pallor · frailty · exhaustion · lethargy · debility · lassitude · malaise · asthenia · loss of appetite · gauntness
malnutrition
Disease from dietary inadequacy
- undernourishmentInsufficient dietary intake
- malabsorptionFailed intestinal nutrient uptake
- nutritional supportAid ensuring adequate nourishment
caloric deficit · protein deficiency · refeeding · supplementation · inanition
cancer
Uncontrolled cell proliferation disease
- AIDSImmune deficiency syndrome
- tuberculosisMycobacterial lung disease
- COPDChronic obstructive pulmonary disease
heart failure · chronic disease · renal failure · sepsis · rheumatoid arthritis · Crohn's disease · cirrhosis · malignancy · inflammatory disease · neoplastic
cytokines
Immune signaling proteins
- inflammationProtective tissue response
- hypermetabolismAbnormally elevated metabolic rate
- proteolysisEnzymatic protein breakdown
lipolysis · interleukin · insulin resistance · energy expenditure · hormonal imbalance
cachexiarobust health
Excellent physical condition
vigor · plumpness · corpulence · thriving · vitality
cachexiaanabolism
Metabolic construction of molecules
recovery · regeneration · restoration · weight gain · convalescence
cachexiaanabolism
Metabolic construction of molecules
weight gain · muscle building · lipogenesis · protein synthesis · metabolic health