tryptamine
Serotonin's chemical backbone
Tryptamine is an organic compound that serves as the structural backbone for a class of psychoactive substances.
The tryptamine structure appears in neurotransmitters like serotonin and melatonin, and in psychedelics like psilocybin and DMT.
In pharmacology and chemistry, tryptamines are discussed as a family: The drug was identified as a synthetic tryptamine.
Powerful naturally occurring hallucinogen
- psilocybinHallucinogenic substance from fungi
- ayahuascaPsychoactive Amazonian plant brew
- LSDPsychedelic hallucinogen
- mescalinePsychoactive cactus alkaloid
trip · visions · hallucinations · mystical · synesthesia · psychedelia · consciousness · set
Fused benzene-pyrrole heterocycle
- metaboliteSubstance from cellular processes
- precursorSomething that comes first
- biosynthesisLiving production of molecules
- decarboxylationCarboxyl group elimination
monoamine · enzyme · substrate · methylation · biogenic · neurochemistry · catecholamine · dopamine
Affecting brain and mood
- alkaloidNitrogenous plant compound
- receptorSignal-receiving molecule
- agonistReceptor-binding trigger molecule
- antagonistOne who opposes another
binding · potency · metabolism · half-life · bioavailability · MAOI · uptake · serotonergic
Psychoactive Amazonian plant brew
- shamanismMediation between worlds
- peyoteHallucinogenic desert succulent
- mycologyScientific study of fungi
- ritualCeremonial set of actions
ceremony · indigenous · traditional · sacred · curandero
Prolonged low state
- anxietyPersistent apprehensive distress
- euphoriaIntense emotional high
- well-beingState of health, contentment
- dysphoriaProfound psychological discomfort
affect · emotion · antidepressant · SSRI · regulation · imbalance · receptor · reuptake
DMT
Powerful naturally occurring hallucinogen
- psilocybinHallucinogenic substance from fungi
- ayahuascaPsychoactive Amazonian plant brew
- LSDPsychedelic hallucinogen
mescaline · trip · visions · hallucinations · mystical · synesthesia · psychedelia · consciousness · set · setting
indole
Fused benzene-pyrrole heterocycle
- metaboliteSubstance from cellular processes
- precursorSomething that comes first
- biosynthesisLiving production of molecules
decarboxylation · monoamine · enzyme · substrate · methylation · biogenic · neurochemistry · catecholamine · dopamine · tyramine
psychoactive
Affecting brain and mood
- alkaloidNitrogenous plant compound
- receptorSignal-receiving molecule
- agonistReceptor-binding trigger molecule
antagonist · binding · potency · metabolism · half-life · bioavailability · MAOI · uptake · serotonergic · dose-response
ayahuasca
Psychoactive Amazonian plant brew
- shamanismMediation between worlds
- peyoteHallucinogenic desert succulent
- mycologyScientific study of fungi
ritual · ceremony · indigenous · traditional · sacred · curandero
depression
Prolonged low state
- anxietyPersistent apprehensive distress
- euphoriaIntense emotional high
- well-beingState of health, contentment
dysphoria · affect · emotion · antidepressant · SSRI · regulation · imbalance · receptor · reuptake · therapeutic
tryptaminecatecholamine
Tyrosine-derived signaling molecule
tyramine · amphetamine · benzylamine · dopamine · norepinephrine