MAOI

Older depression treatment

MAOI is an abbreviation for monoamine oxidase inhibitor, a class of antidepressant drugs.

MAOIs work by blocking an enzyme that breaks down mood-regulating neurotransmitters.

They require strict dietary restrictions—aged cheeses, cured meats, and certain other foods can trigger dangerous blood pressure spikes when combined with MAOIs: She had to give up red wine while on the MAOI.

restrictions

tyramine

Food-derived vasoactive amine

fermented foods · wine · beer · sauerkraut · soy sauce · broad beans · hypertensive crisis · drug interactions · serotonin syndrome · contraindications

pharmacology

selective

Choosing with care

first-generation · transdermal patch · oral · metabolism · half-life

mechanism

serotonin

Mood-regulating brain chemical

enzyme · catecholamine · deamination · substrate · active site · brain chemistry · synaptic · neurochemistry

treatment

social anxiety

Fear of being judged

hypersomnia · augmentation · neurological conditions

Opposites
mechanism of action

MAOISSRI

Antidepressant medication class abbreviation

Prozac · Zoloft · fluoxetine · sertraline · SNRI

Family

MAOIs

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Used worldwide · Timeless · Rated G