pyrrolizidine

Liver-damaging plant compound

Pyrrolizidine is a bicyclic organic compound consisting of two fused five-membered rings with a nitrogen atom at the junction.

The term appears most often in discussions of pyrrolizidine alkaloids—toxic compounds found in certain plants like comfrey and ragwort that can cause liver damage in humans and livestock when consumed.

botanical

comfrey

Bristly herb for healing

groundsel · houndstongue · boneset · rattlebox · weed

toxicity

hepatotoxic

Destructive to liver cells

contamination · toxicosis · cytotoxic · cirrhosis · mutagenic · teratogenic · chronic exposure · lethal dose · bioactivation · detoxification

foodsafety

contamination

Introduction of impurities

regulation · testing · pollen · spices · salad greens · flour · cereals · monitoring · risk assessment · food chain

chemistry

alkaloid

Nitrogenous plant compound

organic compound · saturated · unsaturated · biosynthesis · metabolite · structure · derivative

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