open reading frame

Translatable genetic sequence

An open reading frame is a stretch of DNA or RNA that could potentially encode a protein—it begins with a start codon and continues without interruption until a stop codon.

Geneticists scan genomes for open reading frames to identify possible genes: The software detected several open reading frames in the sequence.

Often abbreviated ORF.

gene-structure

exon

Protein-coding gene segment

promoter · UTR · gene expression

translation

ribosome

Protein synthesis site

amino acids · protein synthesis · tRNA · anticodon · peptide bond · elongation · initiation · termination · decoding

molecular

codon

Base triplet encoding amino

triplet · nonsense mutation

genomics

bioinformatics

Computational analysis of genetic data

Categories
Opposites
coding potential

open reading framejunk DNA

Genomic material without apparent purpose

intron · satellite DNA

reading frame status

open reading frameframeshift mutation

Base addition or loss misaligns codons

nonsense mutation

Family

open, read, frame, opening, reading, reader, opened, framed, unread

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