cyclosporin
Anti-rejection medication
Cyclosporin is an immunosuppressant drug used primarily to prevent organ rejection after transplants.
It works by suppressing the immune system's T-cells, reducing the body's tendency to attack foreign tissue.
Also used to treat severe autoimmune conditions like rheumatoid arthritis and psoriasis.
Also spelled cyclosporine.
Agent reducing bodily defenses
- rejectionDenial of acceptance
- graftIllicit political gain
- organBody's working component
- kidneyBlood-filtering organ
liver · heart · donor · recipient · antirejection · allograft · compatibility · pancreas
Immune system attacks skin cells
- rheumatoidImmune-mediated joint inflammation
- lupusChronic autoimmune disorder
- uveitisUveal layer inflammation
- nephroticOf kidney protein loss
myasthenia · inflammation · flare-up · chronic · T-cells · self-tolerance · autoimmunity · remission
Encased doses of medicine
- oralOf the mouth
- intravenousInto the vein
- ophthalmicRelating to eyes
- microemulsionStable nanoscale oil-water dispersion
bioavailability · absorption · generic · brand · solution · eyedrops · compounded
Chronic elevated arterial pressure
- tremorInvoluntary rhythmic shaking
- hirsutismAbnormal hair growth disorder
- neurotoxicityHarmful effects on nerves
- hyperlipidemiaElevated blood fat levels
Drug fate in body
- metabolismCellular nutrient conversion
- CYP3A4Hepatic drug-processing enzyme
- half-lifePeriod for fifty-percent reduction
- bioavailabilityFraction reaching active circulation
grapefruit · absorption · distribution · clearance · steady-state
immunosuppressant
Agent reducing bodily defenses
kidney · liver · heart · donor · recipient · antirejection · allograft · compatibility · pancreas · lung
psoriasis
Immune system attacks skin cells
- rheumatoidImmune-mediated joint inflammation
- lupusChronic autoimmune disorder
- uveitisUveal layer inflammation
nephrotic · myasthenia · inflammation · flare-up · chronic · T-cells · self-tolerance · autoimmunity · remission · relapse
capsules
Encased doses of medicine
- oralOf the mouth
- intravenousInto the vein
- ophthalmicRelating to eyes
microemulsion · bioavailability · absorption · generic · brand · solution · eyedrops · compounded
hypertension
Chronic elevated arterial pressure
- tremorInvoluntary rhythmic shaking
- hirsutismAbnormal hair growth disorder
- neurotoxicityHarmful effects on nerves
hyperlipidemia · hyperkalemia · monitoring · creatinine · magnesium
pharmacokinetics
Drug fate in body
- metabolismCellular nutrient conversion
- CYP3A4Hepatic drug-processing enzyme
- half-lifePeriod for fifty-percent reduction
bioavailability · grapefruit · absorption · distribution · clearance · steady-state