graft rejection
Body refuses organ
Graft rejection is the immune response that occurs when a transplant recipient's body attacks donated tissue or an organ as foreign.
The recipient's immune system recognizes the graft as not-self and mounts a defense against it, potentially destroying the transplanted material.
Rejection can be acute (occurring shortly after transplant) or chronic (developing over months or years).
Immunosuppressive drugs help prevent rejection but cannot always overcome it: The kidney showed signs of graft rejection within weeks.
- tolerance inductionCreating immunological acceptance of antigens
- organ transplantationSurgical transfer of body parts
- transplant surgeryProcedure replacing damaged organs
- donor organTransplantable body part
- organ failureVital tissue stops functioning
antigen · tissue match · immunosuppressants · T-cell · white blood cells · crossmatching · immune response · immune system · corticosteroids · allograft · cytokine · monoclonal antibodies · donor compatibility · antibody · attack · kidney · tissue typing · foreign
- complicationscomplication, bleeding, paralysis, infections, hemorrhage
- eye complicationsvision loss, blindness, blurred vision, blurry vision, double vision
- Immune Disordersautoimmune disease, lupus, rheumatoid arthritis, multiple sclerosis, type 1 diabetes
- transplantsorgan transplant, liver transplant, bone marrow transplant, kidney transplant, heart transplant
- graftsallograft, autograft, xenograft, homograft, isograft
- skin graftsautograft, allograft, xenograft, grafting, donor site