aplastic
Failing to develop
Aplastic describes tissue or organs that fail to develop normally or that have lost the ability to generate new cells.
The term appears most often in the phrase aplastic anemia, a serious condition in which the bone marrow stops producing enough blood cells.
The patient was diagnosed with aplastic anemia after months of unexplained fatigue and bruising.
In broader medical use, aplastic can characterize any deficient or absent tissue growth.
Blood cell production ceases
- fatigueWeariness from prolonged exertion
- pallorUnhealthy facial whiteness
- weaknessDeficiency in force
- neutropeniaInsufficient neutrophils in blood
leukopenia · petechiae · bruising · bleeding gums · nosebleeds · infections · dizziness · shortness of breath
Drugs reducing body defenses
- cyclosporineImmunosuppressive transplant drug
- bone marrow transplantInfusing healthy hematopoietic cells
- stem cell transplantInfusion of blood-forming precursors
- corticosteroidsInflammation-suppressing steroid medications
transfusion · remission · response · refractory · relapse · supportive care · matched donor · conditioning
Blood cell production process
- hematopoieticProducing blood cells
- bone marrow biopsyTissue sample from skeleton's interior
- stem cellsUndifferentiated cells with regenerative potential
- hypoplasticAbnormally small or incomplete
hematologist · blood counts · erythrocytes · leukocytes · platelets · aspirate
Triggered by pharmaceuticals
- benzeneAromatic hydrocarbon solvent
- radiationEnergy propagation through space
- viralSpreading quickly online
- hepatitisInflammatory liver condition
parvovirus · autoimmune · inherited · congenital · chemical exposure · toxins · pesticides · environmental
bone marrow failure
Blood cell production ceases
neutropenia · leukopenia · petechiae · bruising · bleeding gums · nosebleeds · infections · dizziness · shortness of breath · hemorrhage
immunosuppressants
Drugs reducing body defenses
- cyclosporineImmunosuppressive transplant drug
- bone marrow transplantInfusing healthy hematopoietic cells
- stem cell transplantInfusion of blood-forming precursors
corticosteroids · transfusion · remission · response · refractory · relapse · supportive care · matched donor · conditioning · engraftment
hematopoiesis
Blood cell production process
- hematopoieticProducing blood cells
- bone marrow biopsyTissue sample from skeleton's interior
- stem cellsUndifferentiated cells with regenerative potential
hypoplastic · hematologist · blood counts · erythrocytes · leukocytes · platelets · aspirate
drug-induced
Triggered by pharmaceuticals
- benzeneAromatic hydrocarbon solvent
- radiationEnergy propagation through space
- viralSpreading quickly online
hepatitis · parvovirus · autoimmune · inherited · congenital · chemical exposure · toxins · pesticides · environmental · genetic
aplasticregenerative
Able to renew itself
hyperplastic · proliferative · hematopoietic · myeloproliferative · generative
aplastichypertrophic
Abnormally enlarged through growth
proliferating · thriving · flourishing · developing · growing
aplastichyperplastic
Abnormally increased cell number
plastic · neoplastic · proliferative · hyperactive · hypertrophic
plastic, plaster, plasticity, cytoplasm, dysplasia, protoplasm, neoplasia, hyperplasia, plastid