TNF inhibitors
Autoimmune disease treatment
TNF inhibitors are medications that block tumor necrosis factor, a protein involved in inflammatory responses.
They treat autoimmune conditions like rheumatoid arthritis, Crohn's disease, and psoriasis by suppressing the immune system's attack on healthy tissue.
Common TNF inhibitors include adalimumab (Humira) and infliximab (Remicade).
Also called TNF blockers or anti-TNF agents.
TNF-blocking biologic drug
- biosimilarFollow-on biological medicine
- monoclonal antibodyEngineered protein from cloned cells
- biologicLiving-organism-derived drug
- immunosuppressantAgent reducing bodily defenses
Autoimmune joint disease
- psoriasisImmune system attacks skin cells
- Crohn's diseaseChronic intestinal inflammation disorder
- ulcerative colitisInflammatory bowel condition with sores
- inflammatory bowel diseaseChronic intestinal tract condition
uveitis · autoimmune disease · chronic inflammation · joint stiffness · synovitis · erythema nodosum
Medication into tissue below dermis
- intravenous infusionFluid administered through veins
- loading doseLarge initial medication amount
- combination therapyUsing multiple treatments together
- methotrexateAntifolate chemotherapy agent
Likelihood of disease transmission
- tuberculosis screeningExam for mycobacterial lung disease
- reactivationRestoring to function
- immunosuppressionReduced bodily defense activation
- hepatitis BViral disease attacking liver
Humira
TNF-blocking biologic drug
- biosimilarFollow-on biological medicine
- monoclonal antibodyEngineered protein from cloned cells
- biologicLiving-organism-derived drug
rheumatoid arthritis
Autoimmune joint disease
- psoriasisImmune system attacks skin cells
- Crohn's diseaseChronic intestinal inflammation disorder
- ulcerative colitisInflammatory bowel condition with sores
inflammatory bowel disease · uveitis · autoimmune disease · chronic inflammation · joint stiffness · synovitis · erythema nodosum
subcutaneous injection
Medication into tissue below dermis
- intravenous infusionFluid administered through veins
- loading doseLarge initial medication amount
- combination therapyUsing multiple treatments together
infection risk
Likelihood of disease transmission
- tuberculosis screeningExam for mycobacterial lung disease
- reactivationRestoring to function
- immunosuppressionReduced bodily defense activation
hepatitis B · contraindication · live vaccine · black box warning
- arthritis treatmentsmethotrexate, NSAIDs, ibuprofen, prednisone, corticosteroids
- biologicsbiologics, biologicals, biopharmaceuticals, monoclonal antibodies, monoclonal antibody
- Immune Drugsimmunosuppressants, immunomodulators, immunotherapy, biologics, biologic
- arthritisarthritis, rheumatoid arthritis, osteoarthritis, gout, juvenile arthritis
- Autoimmunityautoimmunity, autoantibodies, self-tolerance, lupus, multiple sclerosis
- immunologyimmune system, immune response, antibodies, antigens, immunity
TNF inhibitorscorticosteroids
Inflammation-suppressing steroid medications
interferons · IL-6 · NSAIDs · prostaglandins · methotrexate
TNF inhibitorscancer immunotherapy
Using immunity to fight malignancy