autoantibodies
Immune self-targeting proteins
Autoantibodies are antibodies that mistakenly target the body's own tissues rather than foreign invaders like bacteria or viruses.
The immune system produces them when it fails to distinguish self from non-self.
Autoantibodies are central to autoimmune diseases: Lupus patients often have autoantibodies against their own DNA.
Blood tests detecting specific autoantibodies help diagnose conditions like rheumatoid arthritis, type 1 diabetes, and thyroid disorders.
Chronic autoimmune disorder
- rheumatoid arthritisAutoimmune joint disease
- type 1 diabetesAutoimmune insulin deficiency disease
- multiple sclerosisAutoimmune demyelinating neurological disease
- thyroiditisThyroid gland inflammation
scleroderma · Hashimoto · celiac disease · vasculitis · pernicious anemia · vitiligo · psoriasis
Accepting your own imperfections
- cross-reactivityAntibody binding to similar antigens
- B-cellsAntibody-secreting immune cells
- plasma cellsAntibody-producing immune cells
- immunoglobulinDefensive blood protein
Solution strength measurement
- serologyStudy of blood antibodies
- screeningEvaluative selection process
- biomarkerMeasurable biological health signal
- diagnosticTest to identify problems
agglutination · sensitivity · specificity · false positive · panel · laboratory · blood test
Immune response inducer
- receptorSignal-receiving molecule
- nuclearOf atomic energy
- cytoplasmicWithin cell's gel-like matrix
- mitochondrialOf cell's energy centers
tissue · DNA · RNA · phospholipid · insulin · collagen · basement membrane · histone
Reduced bodily defense activation
- immunotherapyDisease treatment via body's defenses
- corticosteroidsInflammation-suppressing steroid medications
- biologicsDrugs derived from organisms
- remissionTemporary disease absence
lupus
Chronic autoimmune disorder
- rheumatoid arthritisAutoimmune joint disease
- type 1 diabetesAutoimmune insulin deficiency disease
- multiple sclerosisAutoimmune demyelinating neurological disease
thyroiditis · scleroderma · Hashimoto · celiac disease · vasculitis · pernicious anemia · vitiligo · psoriasis
self-tolerance
Accepting your own imperfections
- cross-reactivityAntibody binding to similar antigens
- B-cellsAntibody-secreting immune cells
- plasma cellsAntibody-producing immune cells
titer
Solution strength measurement
- serologyStudy of blood antibodies
- screeningEvaluative selection process
- biomarkerMeasurable biological health signal
diagnostic · agglutination · sensitivity · specificity · false positive · panel · laboratory · blood test
antigen
Immune response inducer
- receptorSignal-receiving molecule
- nuclearOf atomic energy
- cytoplasmicWithin cell's gel-like matrix
mitochondrial · tissue · DNA · RNA · phospholipid · insulin · collagen · basement membrane · histone · centromere
immunosuppression
Reduced bodily defense activation
- immunotherapyDisease treatment via body's defenses
- corticosteroidsInflammation-suppressing steroid medications
- biologicsDrugs derived from organisms