IL-6
Fever-promoting protein molecule
IL-6, or interleukin-6, is a protein that regulates immune responses and inflammation.
The body produces it during infection, tissue injury, or stress, signaling other immune cells to respond.
Elevated IL-6 levels are associated with chronic inflammatory conditions, autoimmune diseases, and severe infections: Her IL-6 levels were dangerously high during the cytokine storm.
Severe onset period
- chronic inflammationPersistent immune response in tissues
- C-reactive proteinInflammatory biomarker in blood
- feverElevated body temperature
- infectionPathogen invasion causing illness
sepsis · tissue damage · arthritis · autoimmune · rheumatoid arthritis · inflammatory bowel disease · COVID-19 · cachexia
Conveying information nonverbally
- receptorSignal-receiving molecule
- pathwayDesignated route for travel
- cascadeSuccessive downward flow
- immune responseBody fighting foreign threats
cellular communication · transduction · membrane-bound · feedback · cytokine storm
Thymus-matured immune lymphocytes
- B-cellsAntibody-secreting immune cells
- macrophagesLarge pathogen-engulfing immune cells
- monocytesCirculating immune phagocytes
- lymphocytesAdaptive immunity cells
plasma cells · differentiation · proliferation · activation · innate immunity · neutrophils
Blood's watery portion
- plasmaElectrified matter state
- assayCompositional evaluation procedure
- diagnosisIdentification of illness
- prognosisPredicted disease course
detection · screening · quantification · clinical · laboratory · precision medicine · monitoring · predictive
acute phase
Severe onset period
- chronic inflammationPersistent immune response in tissues
- C-reactive proteinInflammatory biomarker in blood
- feverElevated body temperature
infection · sepsis · tissue damage · arthritis · autoimmune · rheumatoid arthritis · inflammatory bowel disease · COVID-19 · cachexia · fibrosis
signaling
Conveying information nonverbally
immune response · cellular communication · transduction · membrane-bound · feedback · cytokine storm
T-cells
Thymus-matured immune lymphocytes
- B-cellsAntibody-secreting immune cells
- macrophagesLarge pathogen-engulfing immune cells
- monocytesCirculating immune phagocytes
lymphocytes · plasma cells · differentiation · proliferation · activation · innate immunity · neutrophils
serum
Blood's watery portion
- plasmaElectrified matter state
- assayCompositional evaluation procedure
- diagnosisIdentification of illness
prognosis · detection · screening · quantification · clinical · laboratory · precision medicine · monitoring · predictive · prognostic
- Cytokinesinterferon, interferons, cytokine storm, G-CSF, CSF
- inflammation markersC-reactive protein, PCT, ferritin, alpha-1 antitrypsin, cytokines
- Interleukins
- MyokinesBDNF
- signaling moleculeshormones, neurotransmitters, histamine, growth factors, prostaglandins
- immunityimmune, immunity, immune system, immune response, immune cells