melatonin

Pineal gland secretion

Melatonin is a hormone produced by the brain's pineal gland that regulates sleep-wake cycles.

The body releases it in response to darkness, signaling that it's time to sleep.

Synthetic melatonin is widely sold as a supplement for insomnia and jet lag: I took some melatonin to help me adjust to the new time zone.

sleep

insomnia

Persistent inability to rest

sleep quality · rest · nap · tiredness · fatigue · deep sleep · REM · dreams · somnolence · wakefulness

circadian

biological clock

Innate cycle regulator

circadian rhythm · entrainment · phase shift · chronotype · light exposure · photoperiod · diurnal · nocturnal · night shift · time zone

hormone

pineal gland

Melatonin-secreting brain structure

biosynthesis · receptor · neuroendocrine · synthesis · regulation · neurotransmitter · enzyme · precursor · blood levels · endogenous

supplement

sleep aid

Substance promoting drowsiness

dosage · milligram · over-the-counter · sublingual · extended-release · synthetic · natural · brand · bottle · timing

therapeutic

sleep disorder

Condition disrupting normal rest

anxiety · antioxidant · neuroprotective · anti-inflammatory · immune function · aging · cancer research · migraine · cluster headache · tinnitus

Categories
Opposites
physiological effect on alertness

melatonincaffeine

Methylxanthine stimulant compound

amphetamines · stimulants · cocaine · ephedrine · nicotine

circadian phase

melatonincortisol

Adrenal steroid regulating stress

sunlight · daylight · blue light · morning light · serotonin

effect on physiological arousal

melatoninadrenaline

Emergency response hormone

epinephrine · cortisol · norepinephrine · stress hormones · dopamine

Phrases
Family

melanin, serotonin, melanocyte, melanism

Familiarity
Top 100,000
Profile
Used worldwide · Timeless · Concrete · Rated G