acetylate
Attach acetyl group
To acetylate is to introduce an acetyl group into a molecule, a fundamental reaction in chemistry and biochemistry.
Aspirin is acetylated salicylic acid.
In biology, acetylation modifies proteins and affects gene expression: Histones are acetylated to regulate DNA transcription.
The noun is acetylation.
Chromosome-packing protein
- chromatinNuclear protein-wrapped genetic material
- lysineEssential amino acid
- nucleosomeHistone-DNA complex
- transcriptionWritten version of speech
regulation · remodeling · HAT · HDAC · enhancer · promoter · silencing · activation
Cellular nutrient conversion
- biotransformationMetabolic chemical conversion
- pharmacokineticsDrug fate in body
- pathwayDesignated route for travel
- cofactorEnzyme-activating compound
substrate · catalysis · mechanism · kinetics · therapeutic · pharmaceutical · detoxification · conjugation
Multi-field technical acronym
- HDACChromatin-compacting enzyme
- transferaseGroup-moving enzyme
- catalystAgent enabling change
- cofactorEnzyme-activating compound
kinetics · inhibitor · activator · recognition · binding
Sharing electrons between atoms
- lysineEssential amino acid
- N-terminalPeptide's amine-bearing end
- reversibleAble to be undone
- dynamicActive and changing
turnover · site-specific · stoichiometry · detection · antibody · mutant · mimic · phosphorylation
Forming esters chemically
- amideCarbonyl-nitrogen functional group
- nucleophileElectron-pair donating species
- hydroxyl-OH functional group
- amineAmmonia-derived organic compound
catalyst · reagent · yield · selectivity · protection · workup · purification · characterization
histone
Chromosome-packing protein
- chromatinNuclear protein-wrapped genetic material
- lysineEssential amino acid
- nucleosomeHistone-DNA complex
transcription · regulation · remodeling · HAT · HDAC · enhancer · promoter · silencing · activation · inheritance
metabolism
Cellular nutrient conversion
- biotransformationMetabolic chemical conversion
- pharmacokineticsDrug fate in body
- pathwayDesignated route for travel
cofactor · substrate · catalysis · mechanism · kinetics · therapeutic · pharmaceutical · detoxification · conjugation · biosynthesis
HAT
Multi-field technical acronym
- HDACChromatin-compacting enzyme
- transferaseGroup-moving enzyme
- catalystAgent enabling change
cofactor · kinetics · inhibitor · activator · recognition · binding
covalent
Sharing electrons between atoms
- lysineEssential amino acid
- N-terminalPeptide's amine-bearing end
- reversibleAble to be undone
dynamic · turnover · site-specific · stoichiometry · detection · antibody · mutant · mimic · phosphorylation · methylation
esterification
Forming esters chemically
- amideCarbonyl-nitrogen functional group
- nucleophileElectron-pair donating species
- hydroxyl-OH functional group
amine · catalyst · reagent · yield · selectivity · protection · workup · purification · characterization · aspirin