Guillain-Barre

Post-infectious nerve damage

Guillain-Barré syndrome is a rare neurological disorder in which the body's immune system attacks the peripheral nerves, causing weakness, numbness, and sometimes paralysis.

It often follows a viral infection and typically progresses rapidly over days or weeks.

Most patients recover, though some experience lasting effects: She was hospitalized with Guillain-Barré after a flu-like illness.

pathophysiology

demyelination

Nerve sheath degradation

axonal · antibodies · nerve damage · neuropathy · myelin sheath · motor neurons · sensory loss · inflammation · peripheral nerves · flaccid paralysis

treatment

immunoglobulin

Defensive blood protein

physical therapy · respiratory support · intubation · tracheostomy · supportive care · blood thinners · pain management · occupational therapy · monitoring · hospitalization

prognosis

recovery

Regaining what was lost

disability · walking · ambulation · long-term · plateau · improvement · outcome · mortality · respiratory failure · wheelchair

diagnosis

lumbar puncture

Extracting cerebrospinal fluid diagnostically

MRI · reflexes · muscle strength · spinal tap · neurological exam · variant · differential diagnosis

triggers

infection

Pathogen invasion causing illness

  • viralSpreading quickly online
  • ZikaMosquito-spread viral infection
  • influenzaAcute viral respiratory infection

Epstein-Barr · cytomegalovirus · gastroenteritis · respiratory illness · vaccination · surgery · diarrhea · fever · upper respiratory · HIV

Opposites
disease course

Guillain-Barremultiple sclerosis

Autoimmune demyelinating neurological disease

transverse myelitis · ALS · brain lesions

direction of progression

Guillain-Barrebotulism

Bacterial food poisoning

tetanus

Familiarity
Top 1,000,000
Profile
Used worldwide · Timeless · Negative · Rated G