amination

Adding nitrogen groups

Amination is a chemical process that introduces an amine group (nitrogen bonded to hydrogen) into a molecule.

The reaction is fundamental in organic chemistry and pharmaceutical manufacturing, where it creates compounds containing nitrogen: Reductive amination is used to synthesize many common drugs.

The reverse process is deamination.

organic synthesis

alkylation

Adding hydrocarbon groups chemically

selectivity · condensation · cyclization · protection · catalyst · yield · ammonia · hydrogenation

biochemical

transaminase

Amino group transfer catalyst

enzyme · catalysis · substrate · cofactor · metabolite · pathway · active site · kinetics · mechanism · intermediate

nitrogen chemistry

ammonia

Acrid nitrogen-hydrogen gas

amide · azide · nitrite · nitrate · basicity · hydrazine

Opposites
chemical transformation direction

aminationdeamination

Amino group removal process

transamination · hydrolysis

Phrases
Family

reductive amination, deamination, transamination

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