sex-linked
Inherited via X/Y
Sex-linked describes a genetic trait carried on a sex chromosome, usually the X chromosome.
Because males have only one X chromosome, they're more likely to express recessive sex-linked traits like color blindness or hemophilia: Hemophilia is a sex-linked disorder that predominantly affects males.
Females, with two X chromosomes, are more often carriers than affected.
disorders
Genetic clotting impairment
- colorblindnessImpaired hue discrimination
- fragile X syndromeGenetic cause of cognitive impairment
- G6PD deficiencyInherited enzyme defect in erythrocytes
- Lesch-Nyhan syndromeHPRT deficiency disorder
chromosomal
Sex-linked genetic structure
- Y-chromosomeMale-determining genetic unit
- dosage compensationEqualizing sex chromosome expression
- SRY geneMammalian male-determination gene
- karyotypeOrganized chromosome display
recessive · dominant · allele · locus · crossing over
hemophilia
Genetic clotting impairment
- colorblindnessImpaired hue discrimination
- fragile X syndromeGenetic cause of cognitive impairment
- G6PD deficiencyInherited enzyme defect in erythrocytes
Lesch-Nyhan syndrome · factor VIII · pedigree · genetic counseling
X-chromosome
Sex-linked genetic structure
- Y-chromosomeMale-determining genetic unit
- dosage compensationEqualizing sex chromosome expression
- SRY geneMammalian male-determination gene
karyotype · recessive · dominant · allele · locus · crossing over
mosaicism
Mixed genetic makeup
- trisomyThree chromosomes, not two
- intersexAtypical sex development
- hormone therapyTreatment using body's messengers