polioviruses
Infantile paralysis agents
Polioviruses are the viruses that cause poliomyelitis, a disease that can paralyze or kill by attacking nerve cells in the spinal cord.
Three types exist, targeted by vaccines developed in the 1950s.
Once widespread, polioviruses have been nearly eradicated through global vaccination campaigns, persisting in only a few countries.
Small intestinal RNA pathogen
- RNA virusPathogen using ribonucleic acid
- replicationAct of duplicating precisely
- mutationPermanent DNA alteration
- fecal-oralTransmission via ingested waste
transmission · incubation · asymptomatic · viremia · shedding · receptor · capsid · genome
Loss of muscle function
- muscle weaknessReduced contractile capacity
- atrophyWasting from disuse
- flaccidityLack of firmness
- paresisPartial loss of movement
paraplegia · quadriplegia · spasticity · neurological · bulbar · meningitis · encephalitis · respiratory failure
Polio vaccine creator
- IPVInjected polio immunization
- inactivatedMade no longer operative
- oralOf the mouth
- immunizationProtective medical injection
boosters · inoculation · trivalent · bivalent · cold chain · schedule · pediatric · herd immunity
Widespread disease occurrence
- endemicNative to one area
- outbreakSudden eruption of trouble
- casesContainers or instances
- incidenceRate of occurrence
prevalence · transmission · sanitation · hygiene · contamination · waterborne · sewage · surveillance
UN health authority
- RotaryInternational humanitarian organization
- UNICEFGlobal youth relief organization
- CDCU.S. public health agency
- surveillanceSystematic observation of subjects
certification · endemic · outbreak response · containment · endgame · last mile
enterovirus
Small intestinal RNA pathogen
- RNA virusPathogen using ribonucleic acid
- replicationAct of duplicating precisely
- mutationPermanent DNA alteration
fecal-oral · transmission · incubation · asymptomatic · viremia · shedding · receptor · capsid · genome
paralysis
Loss of muscle function
- muscle weaknessReduced contractile capacity
- atrophyWasting from disuse
- flaccidityLack of firmness
paresis · paraplegia · quadriplegia · spasticity · neurological · bulbar · meningitis · encephalitis · respiratory failure · iron lung
Salk
Polio vaccine creator
- IPVInjected polio immunization
- inactivatedMade no longer operative
- oralOf the mouth
immunization · boosters · inoculation · trivalent · bivalent · cold chain · schedule · pediatric · herd immunity · antibodies
epidemic
Widespread disease occurrence
incidence · prevalence · transmission · sanitation · hygiene · contamination · waterborne · sewage · surveillance · reporting
WHO
UN health authority
- RotaryInternational humanitarian organization
- UNICEFGlobal youth relief organization
- CDCU.S. public health agency
surveillance · certification · endemic · outbreak response · containment · endgame · last mile
poliovirusespolio vaccine
Immunization against poliomyelitis
Salk vaccine · antibodies · antivirals · immune response · probiotics