haemophilia
Hereditary bleeding condition
Haemophilia is a genetic disorder in which blood fails to clot properly, causing prolonged bleeding from even minor injuries.
The condition results from deficiency of clotting factors and is inherited almost exclusively by males through their mothers.
The spelling haemophilia is British; Americans write hemophilia.
Coagulation protein enabling clotting
- coagulationLiquid solidifying into mass
- thrombinSerine protease enabling coagulation
- fibrinogenPlasma protein for coagulation
- fibrinClot-forming protein
Profuse discharge of blood
- bruisingCausing tissue discoloration
- transfusionTransfer of blood intravenously
- bleeding disorderImpaired blood clotting condition
- internal bleedingBlood pooling inside tissues
nosebleed · hematoma · blood loss · petechiae · wound healing
Masked unless paired identically
- mutationPermanent DNA alteration
- carrierOne that transports
- inheritanceProperty received from ancestors
- chromosomeDNA strand carrying genes
gene therapy · genetic testing · prenatal diagnosis · family history · pedigree · genetic counseling · germline · hereditary
Preventive medical treatment
- infusionSteeping to extract essence
- replacement therapySupplying lacking substances medically
- gene therapyMedical DNA modification treatment
- inhibitorAgent that slows reactions
Treatment restoring bodily function
- multidisciplinaryInvolving several academic fields
- pain managementReducing patient suffering medically
- dental careMaintaining healthy mouths
- quality of lifeGeneral life satisfaction
Moderate in intensity
- moderateLessen intensity or preside
- severeExtremely harsh or strict
- congenitalExisting from birth
- classificationSystematic grouping by traits
factor VIII
Coagulation protein enabling clotting
- coagulationLiquid solidifying into mass
- thrombinSerine protease enabling coagulation
- fibrinogenPlasma protein for coagulation
fibrin · clotting factor · prothrombin · hemostasis · clot formation
hemorrhage
Profuse discharge of blood
- bruisingCausing tissue discoloration
- transfusionTransfer of blood intravenously
- bleeding disorderImpaired blood clotting condition
internal bleeding · nosebleed · hematoma · blood loss · petechiae · wound healing
recessive
Masked unless paired identically
- mutationPermanent DNA alteration
- carrierOne that transports
- inheritanceProperty received from ancestors
chromosome · gene therapy · genetic testing · prenatal diagnosis · family history · pedigree · genetic counseling · germline · hereditary · X-chromosome
prophylaxis
Preventive medical treatment
- infusionSteeping to extract essence
- replacement therapySupplying lacking substances medically
- gene therapyMedical DNA modification treatment
physiotherapy
Treatment restoring bodily function
- multidisciplinaryInvolving several academic fields
- pain managementReducing patient suffering medically
- dental careMaintaining healthy mouths
mild
Moderate in intensity
- moderateLessen intensity or preside
- severeExtremely harsh or strict
- congenitalExisting from birth
- haemo- wordshaemoglobin, haemorrhage, haematology, haemodialysis, haematoma
- bleeding disordersbleeding disorder
haemophiliathrombosis
Clot forming in vessel
thromboembolism · deep vein thrombosis · pulmonary embolism · stroke