estradiol
Primary female estrogen
Estradiol is the primary form of estrogen, a hormone central to female reproductive development and function.
It regulates the menstrual cycle, supports pregnancy, and maintains bone density.
Produced mainly in the ovaries, it's also synthesized in smaller amounts by the adrenal glands and testes.
Pharmaceutical estradiol treats menopause symptoms, hormone deficiency, and is used in gender-affirming care for transgender women.
Estrogen biosynthesis catalyst
- cholesterolWaxy lipid in blood
- precursorSomething that comes first
- cytochromeHeme protein transferring electrons
- enzymeProtein that hastens reactions
synthase · substrate · conversion · pathway · testosterone · theca · adrenal · placental
Egg discharge from ovary
- menstrual cycleMonthly female reproductive process
- follicleSkin cavity growing strands
- ovaryFemale reproductive gland
- uterusFemale reproductive organ
endometrium · fertility · conception · pregnancy · implantation · menstruation · puberty · menarche
Signal-receiving molecule
- steroid hormoneCholesterol-based bodily regulator
- estroneA natural estrogen
- estriolWeakest natural female hormone
- metaboliteSubstance from cellular processes
Supplemental endocrine treatment
- hormone replacement therapySupplementing depleted bodily chemicals
- transdermal patchDrug-releasing skin adhesive
- vaginal ringHormonal birth control insert
- injectionSyringe-delivered dose
bioidentical · conjugated · dosage · prescription · contraceptive · IVF · fertility treatment · hot flashes
Subthalamic regulatory brain region
- pituitaryBrain-base hormone gland
- feedback loopSelf-modifying cyclical process
- gonadotropinHormone stimulating reproductive glands
- LHGonadotropin from pituitary
aromatase
Estrogen biosynthesis catalyst
- cholesterolWaxy lipid in blood
- precursorSomething that comes first
- cytochromeHeme protein transferring electrons
enzyme · synthase · substrate · conversion · pathway · testosterone · theca · adrenal · placental · adipose
ovulation
Egg discharge from ovary
- menstrual cycleMonthly female reproductive process
- follicleSkin cavity growing strands
- ovaryFemale reproductive gland
uterus · endometrium · fertility · conception · pregnancy · implantation · menstruation · puberty · menarche · menopause
receptor
Signal-receiving molecule
- steroid hormoneCholesterol-based bodily regulator
- estroneA natural estrogen
- estriolWeakest natural female hormone
metabolite · lipophilic · genomic · signaling
HRT
Supplemental endocrine treatment
- hormone replacement therapySupplementing depleted bodily chemicals
- transdermal patchDrug-releasing skin adhesive
- vaginal ringHormonal birth control insert
injection · bioidentical · conjugated · dosage · prescription · contraceptive · IVF · fertility treatment · hot flashes · bone density
hypothalamus
Subthalamic regulatory brain region
- pituitaryBrain-base hormone gland
- feedback loopSelf-modifying cyclical process
- gonadotropinHormone stimulating reproductive glands
LH · secretion · homeostasis · glandular · bioavailable
- hormonestestosterone, insulin, hormone, cortisol, progesterone
- menopausehot flashes, night sweats, hot flushes, perimenopause, postmenopause
- reproductive hormonesprogesterone, testosterone, androgens, androgen, LH
- cyclic compoundscyclopropane, cyclopentane, cyclohexane, benzene, naphthalene
- estrogen therapyestriol, estrone, Premarin
- estrogensestrone, estriol, diethylstilbestrol, DES, Premarin