diethylstilbestrol
Banned pregnancy drug
Diethylstilbestrol is a synthetic estrogen prescribed from the 1940s through 1970s to prevent miscarriage.
The drug was later found to cause cancer and reproductive abnormalities in children exposed in utero, making it a landmark case in pharmaceutical regulation.
Often abbreviated DES.
Symmetric-key block cipher
- pharmaceuticalManufactured medicinal compound
- medicationTherapeutic substance for illness
- prescriptionMedical dispensing authorization
- pillSolid medicine dose
tablet · dosage · regimen · pharmacology · teratogen · carcinogen · contraindications · efficacy
Female reproductive hormone
- estradiolPrimary natural estrogen hormone
- receptorSignal-receiving molecule
- bindingLegally or morally required
- affinityNatural liking or attraction
agonist · feminization · reproductive · hormonal · breast · ovary · uterus · cervix
Legal dispute process
- lawsuitCivil court proceeding
- class actionLawsuit filed for many
- malpracticeHarmful professional negligence
- negligenceFailure to exercise care
scandal · thalidomide · regulation · FDA · banned · public health · awareness · activism
Inability to reproduce
- ectopic pregnancyImplantation outside the uterus
- preterm birthDelivery before 37 weeks
- vaginal cancerMalignancy of birth canal
- breast cancerMalignant growth in mammary glands
birth defects · transgenerational · prenatal exposure · teratogenic · carcinogenic
DES
Symmetric-key block cipher
- pharmaceuticalManufactured medicinal compound
- medicationTherapeutic substance for illness
- prescriptionMedical dispensing authorization
pill · tablet · dosage · regimen · pharmacology · teratogen · carcinogen · contraindications · efficacy · indication
estrogen
Female reproductive hormone
- estradiolPrimary natural estrogen hormone
- receptorSignal-receiving molecule
- bindingLegally or morally required
affinity · agonist · feminization · reproductive · hormonal · breast · ovary · uterus · cervix · vaginal
litigation
Legal dispute process
- lawsuitCivil court proceeding
- class actionLawsuit filed for many
- malpracticeHarmful professional negligence
negligence · scandal · thalidomide · regulation · FDA · banned · public health · awareness · activism · accountability
infertility
Inability to reproduce
- ectopic pregnancyImplantation outside the uterus
- preterm birthDelivery before 37 weeks
- vaginal cancerMalignancy of birth canal
breast cancer · birth defects · transgenerational · prenatal exposure · teratogenic · carcinogenic
- carcinogensasbestos, benzene, formaldehyde, arsenic, tobacco smoke
- Drug Scandalsthalidomide, fen-phen, OxyContin, opioid epidemic, opioid crisis
- endocrine disruptorsBPA, phthalates, parabens, PCBs, dioxins
- estrogensestrogen, estradiol, estrone, estriol, DES
- hormone therapyhormone therapy, estradiol, hormone replacement, HRT, estrogen therapy
- Phenolicsphenol, catechins, flavone, flavonoids, quercetin