tolerance induction

Training immune acceptance

Tolerance induction is the process of training the immune system to accept a substance it would otherwise attack.

In medicine, this applies to preventing organ transplant rejection or treating autoimmune diseases and allergies.

The goal is to make the body tolerant of specific proteins or tissues: Tolerance induction could eliminate the need for lifelong immunosuppressant drugs.

Related

regulatory T cells · thymus · negative selection · unresponsiveness · desensitization · allergy shots · monoclonal antibodies · apoptosis · oral · organ transplant · foreign · lymphocytes · regulatory · rejection · graft · central · immune · T-cells

Categories
Opposites
immune response outcome

tolerance inductionimmunization

Protective medical injection

sensitization · immunostimulation · vaccination · anaphylaxis

therapeutic goal in transplantation/autoimmunity

tolerance inductiongraft rejection

Immune destruction of transplant

transplant rejection · autoimmunity

immune activation state

tolerance inductionimmune suppression

Reduced defensive response capability

immunosuppression · inflammatory response

Family

tolerance, tolerant, induce, induction

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