Howell-Jolly bodies
Nuclear debris inclusions
Howell-Jolly bodies are small, round remnants of nuclear material visible in red blood cells under a microscope.
They normally get filtered out by the spleen, so their presence in a blood smear suggests the spleen is absent, damaged, or not functioning properly.
Named for the physicians William Howell and Justin Jolly, who described them independently.
- spleenBlood-filtering abdominal organ
- red blood cellsOxygen-transporting components of circulation
- anemiaRed cell deficiency
- blood smearThin layer for microscopy
- nucleusCentral controlling part
remnants · sickle cell · hematology · microscope · purple · dots · inclusions · erythrocytes · splenectomy · DNA · fragments · peripheral · staining · hemolytic · pathology · stippling · malaria · thalassemia
- Blood Abnormalitiessickle cells
- Blood Smearsblood smear, thin film, smear, Giemsa stain, glass slide
- cell inclusionsferritin, glycogen, melanin, amyloid, crystalloids
- blood disordersanemia, sickle cell anemia, sickle cell disease, thalassemia, leukemia
- cell pathologyapoptosis, necrosis, cell death, cell lysis, DNA damage
- spleenspleen, splenectomy, splenic, enlarged spleen, ruptured spleen
Jolly, bodies, bodily, bodied, disembodied, embody, embodied, embodiment, anybody