rDNA
Engineered genetic material
rDNA stands for recombinant DNA—genetic material created by combining DNA sequences from different sources, often different species.
The technology allows scientists to insert genes from one organism into another: rDNA techniques produced the first synthetic human insulin.
The term also appears as "recombinant DNA" or "r-DNA." In a separate context, rDNA can refer to ribosomal DNA, the genes encoding ribosomal RNA.
Pancreatic glucose-regulating hormone
- human growth hormonePituitary peptide promoting development
- interferonImmune response protein
- monoclonal antibodiesIdentical lab-cloned immune proteins
- vaccinesPreparations conferring immunity
biopharmaceuticals · golden rice · factor VIII · hepatitis B vaccine · biofuels · biosynthesis · diagnostics
Self-replicating DNA circle
- vectorQuantity with direction
- cloningMaking identical copies
- transformationThorough change in form
- ligationSurgical binding of vessels
gene splicing · insertion · expression · host cell · transgenic · bioreactor · fermentation · promoter
Medical DNA modification treatment
- viral vectorVirus repurposed for therapy
- CRISPRGene-editing molecular machinery
- Cas9DNA-cutting enzyme
- gene editingTargeted DNA alteration
cystic fibrosis · hemophilia · muscular dystrophy · immunodeficiency · clinical trial · germline · in vivo · precision medicine
Study of entire genetic sequences
- sequencingDetermining element order
- PCRDNA amplification technique
- Southern blotDNA transfer and detection method
- screeningEvaluative selection process
Protection from biological hazards
- GMO labelingMarking genetically altered products
- bioethicsMoral philosophy for medicine
- containmentPreventing hostile expansion
- FDA approvalOfficial drug safety certification
public perception · moratorium · risk assessment · informed consent · patent · intellectual property
insulin
Pancreatic glucose-regulating hormone
- human growth hormonePituitary peptide promoting development
- interferonImmune response protein
- monoclonal antibodiesIdentical lab-cloned immune proteins
vaccines · biopharmaceuticals · golden rice · factor VIII · hepatitis B vaccine · biofuels · biosynthesis · diagnostics
plasmid
Self-replicating DNA circle
- vectorQuantity with direction
- cloningMaking identical copies
- transformationThorough change in form
ligation · gene splicing · insertion · expression · host cell · transgenic · bioreactor · fermentation · promoter · antibiotic resistance
gene therapy
Medical DNA modification treatment
- viral vectorVirus repurposed for therapy
- CRISPRGene-editing molecular machinery
- Cas9DNA-cutting enzyme
gene editing · cystic fibrosis · hemophilia · muscular dystrophy · immunodeficiency · clinical trial · germline · in vivo · precision medicine · lentivirus
genomics
Study of entire genetic sequences
- sequencingDetermining element order
- PCRDNA amplification technique
- Southern blotDNA transfer and detection method
screening · mutagenesis · gene mapping · hybridization · probe
biosafety
Protection from biological hazards
- GMO labelingMarking genetically altered products
- bioethicsMoral philosophy for medicine
- containmentPreventing hostile expansion
FDA approval · public perception · moratorium · risk assessment · informed consent · patent · intellectual property