immune-mediated

Defense system caused

Immune-mediated describes conditions or reactions caused by the body's own immune system.

An immune-mediated disease occurs when immune responses attack healthy tissue or overreact to harmless substances: immune-mediated hemolytic anemia, immune-mediated arthritis.

The term appears frequently in veterinary and medical contexts to distinguish conditions driven by immune dysfunction from those caused by infection or injury.

pathology

autoimmune

Body attacks itself

reaction · antibody · cytokine · T-cell · B-cell · hypersensitivity · vasculitis · nephritis · hemolytic · encephalitis

treatment

immunosuppression

Reduced bodily defense activation

methotrexate · cyclosporine · remission · flare · refractory · maintenance · induction · tapering · monoclonal · inhibitor

mechanism

response

Answer to stimulus

signaling · complement · immunoglobulin · lymphocyte · macrophage · neutrophil · histamine · interleukin · interferon · cytotoxic

Opposites
disease causation mechanism

immune-mediatedinfectious

Able to spread disease

genetic · hereditary · congenital · mechanical · bacterial

infectious vs. autoimmune etiology

immune-mediatedinfectious

Able to spread disease

bacterial · viral · fungal · parasitic · microbial

immune system involvement

immune-mediatedpassive

Not actively participating

structural

Family

mediator, immune, immunity, mediate, mediation, intermediate, immunize, immunology

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