hydrochloride

Drug stability compound

Hydrochloride describes a chemical compound formed when hydrochloric acid combines with an organic base, typically a drug or medication.

Many pharmaceuticals are formulated as hydrochloride salts because this form dissolves more readily and absorbs better in the body: oxycodone hydrochloride, fluoxetine hydrochloride.

The term appears on medication labels and in pharmacology.

pharmaceutical

drug

Active chemical compound

injection · prescription · formulation · compound · dosage · antidepressant · analgesic · antihistamine · sedative · bronchodilator

solubility

dissolution

Breaking up completely

pH · concentration · saturation · precipitate · polarity · partition · diffusion · bioavailability · soluble · insoluble

chemistry

salt

Sodium chloride compound

  • crystallineClear, ordered, brilliant
  • ionCharged atom or molecule
  • acidLow-pH chemical compound

base · amine · synthesis · purification · precipitation · neutralization · titration · stoichiometry · conversion · conjugate

pharmacology

bioavailability

Fraction reaching active circulation

agonist · antagonist · receptor · inhibitor · metabolite · efficacy · potency · dose-response · half-life · clearance

stability

degradation

Decline in condition

hydrolysis · crystallinity · polymorphism · packaging · temperature · humidity · inertness · decomposition · impurity · expiration

Opposites
salt form vs free base

hydrochloridefreebase

Desalted cocaine for smoking

free base · unsalted

salt form type

hydrochloridesulfate

Acidic salt compound

phosphate · citrate · tartrate · maleate · acetate

Phrases
Family

hydrochloric

Familiarity
Top 500,000
Profile
Used worldwide · Timeless · Concrete · Rated G