furanocoumarins

Light-activated plant toxins

Furanocoumarins are organic compounds found in certain plants—particularly citrus fruits, celery, parsley, and figs—that can cause skin reactions when exposed to sunlight.

This phototoxic effect makes skin burn or blister after contact with the plant followed by sun exposure, a condition called phytophotodermatitis.

Grapefruit juice contains furanocoumarins that interfere with drug metabolism, which is why medication labels sometimes warn against grapefruit consumption.

phototoxicity

sunburn

UV-induced skin inflammation

dermatitis · burns · erythema · hyperpigmentation · lime · celery · parsnip · fig · meadow grass · angelica

therapeutic

PUVA therapy

Light-activated skin treatment

repigmentation · dermatology · photomedicine · topical application · dosimetry · treatment protocol

biochemistry

linear

Arranged in straight succession

DNA crosslinking · intercalation · cytotoxicity

dietary

grapefruit juice

Pressed citrus drink, bitter

pomelo · Seville orange · celery root · parsley · carrot · fennel · dill · coriander · cumin · food safety

Categories
Opposites
phytochemical class

furanocoumarinsflavonoids

Polyphenolic plant metabolites

alkaloids · terpenes · carotenoids · saponins · tannins

photobiological effect

furanocoumarinssunscreens

UV-protective skin applications

melanin · antioxidants · carotenoids

Family

furan, coumarin

Familiarity
Top 2,000,000
Profile
Used worldwide · Timeless · Concrete · Rated G