DNA crosslinking
Helix strands fused
DNA crosslinking is the formation of chemical bonds between strands of DNA, either linking the two strands of a double helix together or connecting distant parts of the same strand.
Crosslinks can occur naturally or be induced by certain chemicals and radiation.
In medicine, crosslinking agents are used in chemotherapy to prevent cancer cells from replicating their DNA.
Unrepaired crosslinks can cause mutations or cell death.
- DNAHereditary code molecule
- mutationPermanent DNA alteration
- chemotherapyAnti-cancer drug treatment
- cancer treatmentMedical intervention for malignancy
- repairRestore to working order
damage · helix · strand · base pair · replication · alkylating · adduct · toxicity · mutagenic · cancer · nitrogen mustard · mustard gas · covalent · nucleotide · double helix · carcinogen · UV light · bonds
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