POMC
Pituitary peptide precursor
POMC stands for proopiomelanocortin, a precursor protein that the body breaks down into several hormones, including those that regulate stress response, skin pigmentation, and appetite.
POMC is central to understanding conditions like obesity and adrenal disorders: POMC gene mutations can cause severe early-onset obesity.
The term appears mainly in endocrinology and neuroscience research.
Adrenal-stimulating pituitary secretion
- adrenocorticotropicStimulating outer adrenal layer
- endorphinBody's natural analgesic
Inactive hormonal precursor
- cleavageTendency to split cleanly
- precursorSomething that comes first
- polypeptideAmino acid polymer
- processingSystematic operation on data
Brain-base hormone gland
- hypothalamusSubthalamic regulatory brain region
- secretionSubstance released by glands
- CRHStress-axis initiating peptide
- neuroendocrineNerve-gland interaction system
Desire for food
- satietyState of being full
- obesityExcess body fat condition
- analgesiaAbsence of sensation
- pigmentationNatural tissue coloring
feeding · reward · stress · inflammation · metabolism · homeostasis
Receptor-binding trigger molecule
- antagonistOne who opposes another
- bindingLegally or morally required
- signalingConveying information nonverbally
ACTH
Adrenal-stimulating pituitary secretion
- adrenocorticotropicStimulating outer adrenal layer
- endorphinBody's natural analgesic
prohormone
Inactive hormonal precursor
- cleavageTendency to split cleanly
- precursorSomething that comes first
- polypeptideAmino acid polymer
pituitary
Brain-base hormone gland
- hypothalamusSubthalamic regulatory brain region
- secretionSubstance released by glands
- CRHStress-axis initiating peptide
appetite
Desire for food
pigmentation · feeding · reward · stress · inflammation · metabolism · homeostasis
agonist
Receptor-binding trigger molecule
- antagonistOne who opposes another
- bindingLegally or morally required
- signalingConveying information nonverbally
- MelanocortinsACTH, proopiomelanocortin
- Peptide Hormonesoxytocin, vasopressin, insulin, glucagon, gastrin
- POMC Peptidesproopiomelanocortin, ACTH
- diet aidsphentermine, semaglutide, appetite suppressant, fat burner, meal replacement
- proenzymeszymogen, proenzyme, pepsinogen, chymotrypsinogen, prothrombin