Bartter syndrome
Renal potassium depletion
Bartter syndrome is a rare inherited kidney disorder in which the kidneys fail to reabsorb salt properly, leading to low potassium, muscle weakness, and growth problems.
It typically appears in infancy or childhood.
Named after the American endocrinologist Frederic Bartter, who described the condition in 1962.
Excessive urine production condition
- muscle weaknessReduced contractile capacity
- fatigueWeariness from prolonged exertion
- crampsInvoluntary muscle tightening
- dehydrationExcessive fluid loss
vomiting · constipation · tetany · salt craving · failure to thrive · developmental delay · low blood pressure
Adrenal hormone controlling electrolytes
- hormonal imbalanceIrregular glandular secretion levels
Received from forebears
- mutationPermanent DNA alteration
- geneHereditary information unit
- chromosomeDNA strand carrying genes
- hereditaryPassed through generations
genotype · phenotype · alleles · carrier · familial · consanguinity · genetic testing · prenatal diagnosis
Of earliest infancy
- antenatalBefore birth
- prenatalBefore birth
- infancyEarliest period of life
- prematurityState of being underdeveloped
polyuria
Excessive urine production condition
- muscle weaknessReduced contractile capacity
- fatigueWeariness from prolonged exertion
- crampsInvoluntary muscle tightening
dehydration · vomiting · constipation · tetany · salt craving · failure to thrive · developmental delay · low blood pressure
aldosterone
Adrenal hormone controlling electrolytes
- hormonal imbalanceIrregular glandular secretion levels
nephron
Kidney's filtration unit
- kidney stonesMineral formations in organs
inherited
Received from forebears
- mutationPermanent DNA alteration
- geneHereditary information unit
- chromosomeDNA strand carrying genes
hereditary · genotype · phenotype · alleles · carrier · familial · consanguinity · genetic testing · prenatal diagnosis · genomics
electrolyte imbalance
Abnormal blood mineral levels
- electrolyte replacementRestoring lost body salts
neonatal
Of earliest infancy
indomethacin
Nonsteroidal anti-inflammatory drug
- NSAIDsOver-the-counter pain class
- SyndromesGuillain-Barre, restless leg, irritable bowel, IBS, chronic fatigue
- Kidney Diseaseskidney disease, kidney failure, chronic kidney disease, renal failure, nephropathy
- channelopathies
- potassium disordershyperkalemia, high potassium, potassium deficiency, potassium supplements
- mineral disordersiron deficiency, calcium deficiency, magnesium deficiency, potassium deficiency, hypocalcemia
- Fluid Imbalancesdehydrated, edema, fluid loss, fluid retention, overhydration