frontotemporal
Forehead and temple
Frontotemporal refers to the front and side regions of the brain—the frontal and temporal lobes.
The term appears almost exclusively in medical contexts, particularly in frontotemporal dementia, a group of brain disorders affecting personality, behavior, and language.
Unlike Alzheimer's, frontotemporal dementia often strikes people in their fifties or sixties.
Reduced behavioral restraint
- apathyAbsence of feeling
- impulsivityActing without considering consequences
- compulsivityDriven to repeat actions
- perseverationInvoluntary repetition of responses
Before the frontal lobe
- cortexOrgan's external tissue
- lobesRounded projecting parts
- gyrusCerebral cortex ridge
- sulcusGroove in tissue
hemisphere · insular · neocortex · fusiform · amygdala · cerebral · neuroanatomy
Wasting from disuse
- neurodegenerationProgressive loss of neurons
- neuropathologyStudy of nervous system diseases
- biomarkersMeasurable disease indicators
- autopsyMedical examination after death
Neurological language impairment
- anomiaInability to recall words
- word-findingAccessing stored vocabulary
- comprehensionMental understanding of meaning
- circumlocutionIndirect, wordy expression
Permanent DNA alteration
- hereditaryPassed through generations
- familialPertaining to relatives
- penetranceGenotype-to-phenotype expression ratio
- sporadicOccurring irregularly, infrequently
disinhibition
Reduced behavioral restraint
- apathyAbsence of feeling
- impulsivityActing without considering consequences
- compulsivityDriven to repeat actions
prefrontal
Before the frontal lobe
sulcus · hemisphere · insular · neocortex · fusiform · amygdala · cerebral · neuroanatomy
atrophy
Wasting from disuse
- neurodegenerationProgressive loss of neurons
- neuropathologyStudy of nervous system diseases
- biomarkersMeasurable disease indicators
aphasia
Neurological language impairment
- anomiaInability to recall words
- word-findingAccessing stored vocabulary
- comprehensionMental understanding of meaning
diagnosis
Identification of illness
- prognosisPredicted disease course
- caregivingAttending to dependents
mutation
Permanent DNA alteration
- hereditaryPassed through generations
- familialPertaining to relatives
- penetranceGenotype-to-phenotype expression ratio