ferroptosis
Iron-dependent cell demise
Ferroptosis is a form of cell death driven by iron-dependent accumulation of lipid damage.
Unlike apoptosis, which is orderly and programmed, ferroptosis results from unchecked oxidative stress in cell membranes.
The process has attracted research interest for its role in cancer, neurodegeneration, and organ injury: Inhibiting ferroptosis may protect neurons after stroke.
Localized cell death
- autophagyCellular self-degradation process
- cytotoxicityHarmfulness to living cells
- inflammationProtective tissue response
- pathologyStudy of disease processes
Progressive loss of neurons
- cancer therapyTreatment for malignant disease
- Alzheimer'sDegenerative brain disease
- Parkinson'sNeurodegenerative motor disorder
- Huntington'sInherited neurodegenerative condition
cardiomyopathy · stroke · drug resistance · traumatic brain injury · atherosclerosis
glutathione
Sulfur-containing cellular antioxidant
necrosis
Localized cell death
- autophagyCellular self-degradation process
- cytotoxicityHarmfulness to living cells
- inflammationProtective tissue response
neurodegeneration
Progressive loss of neurons
- cancer therapyTreatment for malignant disease
- Alzheimer'sDegenerative brain disease
- Parkinson'sNeurodegenerative motor disorder
Huntington's · cardiomyopathy · stroke · drug resistance · traumatic brain injury · atherosclerosis
BSO
Hub's symphony orchestra
vitamin E
Fat-soluble antioxidant nutrient
- N-acetylcysteineCysteine-derived mucolytic compound
- Cell Deathnecrosis, Bcl-2, Bad, extrinsic pathway, A1
- cell damagecell damage, cell death, cell lysis, necrosis, cytotoxicity
- cytotoxicitycytotoxicity, cytotoxins, cell death, necrosis, lysis
- Redox Biologyfree radical, superoxide, hydrogen peroxide, glutathione, antioxidant
- cell lysislysis, cytolysis, cell lysis, osmotic lysis, hemolysis
- Cell StressDNA damage, hypoxia, cold shock, mechanical stress, free radicals