esterase

Ester bond breaker

An esterase is an enzyme that catalyzes the breakdown of esters into an acid and an alcohol through a reaction with water.

These enzymes play essential roles in metabolism, digestion, and detoxification processes throughout the body.

Different types of esterases target specific ester bonds, such as lipases that break down fats and cholinesterases that regulate neurotransmitters.

The term appears frequently in biochemistry and pharmacology contexts.

biochemistry

hydrolysis

Water-induced bond cleavage

cholesterol · biotransformation · detoxification · drug metabolism · lipase · serine · organophosphate · triglyceride · phospholipid · neurotransmitter

catalysis

active site

Enzyme region binding substrates

specificity · mechanism · turnover · Michaelis-Menten · activation energy · induced fit · cofactor

structure

protein

Folded amino chain

histidine · aspartate · active site · glycoprotein · subunit · dimer · crystallography

classification

hydrolase

Enzyme cleaving via water

Opposites
enzymatic function

esterasesynthase

Bond-forming enzyme

ligase · transferase · polymerase · lipase · hydrolase

Family

cholinesterase

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