phosphatase

Dephosphorylating cellular catalyst

A phosphatase is an enzyme that removes phosphate groups from molecules, the opposite of a kinase.

Phosphatases regulate countless cellular processes by switching proteins between active and inactive states: Alkaline phosphatase levels indicate liver function.

The term appears frequently in biochemistry and medical diagnostics.

biochemistry

hydrolysis

Water-induced bond cleavage

kinase · ATP · ADP · Michaelis-Menten · turnover · specificity

regulation

inhibition

Mental check on behavior

homeostasis · gene expression · oncogene · tumor suppressor · apoptosis

laboratory

assay

Compositional evaluation procedure

electrophoresis · chromatography · mass spectrometry · crystal structure · mutagenesis · liver function test

Opposites
enzymatic function

phosphatasekinase

Phosphate-transferring enzyme

tyrosine kinase

Family

phosphate, phosphorus, phosphates, phosphoric, phosphorous, phosphorylated, calcium phosphate

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