ligase
Bond-forming enzyme
Ligase is an enzyme that catalyzes the joining of two molecules, typically by forming a new chemical bond.
In molecular biology, DNA ligase is essential for replication and repair, sealing breaks in the DNA backbone: The ligase joins the Okazaki fragments together.
Ligases are fundamental tools in genetic engineering for splicing DNA sequences.
DNArepair
Complete DNA backbone cleavage
- recombinationGenetic material exchange process
- Okazaki fragmentsShort DNA replication pieces
- DNA synthesisConstructing genetic material
- sealingMaking impermeable
molecularbiology
Making identical copies
- gene splicingCombining DNA from organisms
- recombinant DNALab-fused genetic sequences
- transformationThorough change in form
- DNA manipulationAltering genetic sequences
biochemistry
B7, a metabolic cofactor
- biosynthesisLiving production of molecules
- anabolismMetabolic construction of molecules
double-strand break
Complete DNA backbone cleavage
- recombinationGenetic material exchange process
- Okazaki fragmentsShort DNA replication pieces
- DNA synthesisConstructing genetic material
cloning
Making identical copies
- gene splicingCombining DNA from organisms
- recombinant DNALab-fused genetic sequences
- transformationThorough change in form
biotin
B7, a metabolic cofactor
- biosynthesisLiving production of molecules
- anabolismMetabolic construction of molecules
condensation
Vapor turning to liquid
- active siteEnzyme region binding substrates
- torn ligamentDamaged joint-stabilizing tissue
- ligament tearRuptured joint connector
- tubal ligationFallopian tube severance surgery
- suspensory ligamentFibers holding ocular lens
- anterior cruciate ligamentKnee's rotational stability band
- cruciate ligamentKnee's cross-shaped stabilizers