cholinesterase

Acetylcholine breakdown catalyst

Cholinesterase is an enzyme that breaks down acetylcholine, a neurotransmitter essential for nerve impulse transmission.

The body produces two main types: acetylcholinesterase, found at nerve synapses, and butyrylcholinesterase, found in blood plasma.

Certain pesticides and nerve agents work by inhibiting cholinesterase, causing acetylcholine to accumulate and overstimulate nerves.

Medical professionals measure cholinesterase levels to assess pesticide exposure or to evaluate liver function, since the liver produces the plasma form.

inhibition

organophosphates

Phosphorus-based toxic compounds

sarin · poisoning · toxicology · antidotes · atropine · pralidoxime · insecticides · irreversible · reversible · reactivation

neurotransmission

synapse

Nerve signal crossing point

signal · transmission · vesicle · nicotinic · neural · degradation · hydrolysis · nerve impulse

enzyme

hydrolysis

Water-induced bond cleavage

serine · biocatalyst · proteins · amino acids · biochemistry · metabolism · reaction · ester · organophosphate · assay

clinical

anesthesia

Induced loss of feeling

biomarker · deficiency · screening · diagnosis

Opposites
substrate relationship

cholinesteraseacetylcholine

Neurotransmitter for muscles and memory

choline · acetyl-CoA

pharmacological effect

cholinesteraseanticholinesterase

Substance preventing acetylcholine degradation

Family

choline, acetylcholine, esterase

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