pyrogen
Substance causing fever
A pyrogen is a substance that causes fever when introduced into the body.
The term appears most often in medical and pharmaceutical contexts, where manufacturers must ensure that injectable drugs and IV fluids are pyrogen-free: The batch was rejected due to pyrogen contamination.
Bacterial toxins are common pyrogens, but the body also produces its own in response to infection.
Having a fever
- hyperthermiaDangerously elevated body temperature
- chillsShivering spells from illness
- sweatingMoisture through pores
- shiveringInvoluntary bodily trembling
temperature · malaise · thermometer · illness · infection · sepsis · typhoid · malaria
Bacterial wall toxin
- exotoxinPoison bacteria secrete
- bacteriaNucleus-free single-celled organisms
- virusMicroscopic infectious agent
- pathogenDisease-causing microorganism
microorganism · antigen · toxoid · adjuvant · infectious agent · immunogenic · antigenic · contamination
Absence of microbes or fertility
- contaminationIntroduction of impurities
- endotoxinBacterial wall toxin
- injectableAdministered via needle
- parenteralNot via alimentary canal
quality control · USP · filtration · autoclave · validation · testing
Immune signaling proteins
- prostaglandinsLipid-derived signaling compounds
- leukocytesImmune cells in blood
- immune responseBody fighting foreign threats
- swellingAbnormal tissue enlargement
redness · acute · chronic · proinflammatory · immunopathology · hypothalamus · thermoregulation
Immune signaling proteins
- interferonImmune response protein
- prostaglandinsLipid-derived signaling compounds
- hypothalamusSubthalamic regulatory brain region
- thermoregulationMaintaining stable internal heat
immune response · proinflammatory · leukocytes · macrophages · monocytes
febrile
Having a fever
- hyperthermiaDangerously elevated body temperature
- chillsShivering spells from illness
- sweatingMoisture through pores
shivering · temperature · malaise · thermometer · illness · infection · sepsis · typhoid · malaria · flu
endotoxin
Bacterial wall toxin
- exotoxinPoison bacteria secrete
- bacteriaNucleus-free single-celled organisms
- virusMicroscopic infectious agent
pathogen · microorganism · antigen · toxoid · adjuvant · infectious agent · immunogenic · antigenic · contamination
sterility
Absence of microbes or fertility
- contaminationIntroduction of impurities
- endotoxinBacterial wall toxin
- injectableAdministered via needle
parenteral · quality control · USP · filtration · autoclave · validation · testing
cytokines
Immune signaling proteins
- prostaglandinsLipid-derived signaling compounds
- leukocytesImmune cells in blood
- immune responseBody fighting foreign threats
swelling · redness · acute · chronic · proinflammatory · immunopathology · hypothalamus · thermoregulation
cytokines
Immune signaling proteins
- interferonImmune response protein
- prostaglandinsLipid-derived signaling compounds
- hypothalamusSubthalamic regulatory brain region
thermoregulation · immune response · proinflammatory · leukocytes · macrophages · monocytes
pyrogenantipyretic
Fever-reducing agent
fever reducer · cryogen · acetaminophen · ibuprofen · aspirin