kill off

End them all

To kill off is to eliminate completely or destroy one by one until none remain.

A disease might kill off an entire species.

Writers kill off characters—removing them permanently from a story, often dramatically.

Companies kill off product lines.

The "off" emphasizes finality: not just killing, but finishing the job.

exterminate

eradicate

Destroy completely, utterly

obliterate · extinguish · destroy · decimate · liquidate · purge · root out · stamp out · dispatch · do away with

suppress

quash

Suppress or nullify

squash · crush · quell · stamp out · snuff out · extinguish · silence · put an end to · terminate · end

extinction

species

Finest taxonomic rank

vanish · disappear · biodiversity · habitat · overhunting · deforestation · die out · mass extinction · dodo · passenger pigeon

cull

herd

Grazing animals together

wildlife · overpopulation · population control · harvesting · sustainable · ecosystem · balance · flock · stock · management

narrative

character

Nature, symbol, or role

showrunner · finale · written out · dramatic death · fan favorite · series · cast · departure · script · episode

Opposites
survival/existence

kill offspare

Held in reserve

save · rescue · preserve · protect · revive

population dynamics

kill offrepopulate

Fill again with inhabitants

breed · propagate · multiply · replenish · reintroduce

creative/narrative context

kill offresurrect

Restore after ending

introduce · write in · bring back · spare · bring in

Family

off, kill, killing, killed

Familiarity
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Known to kids · Used worldwide · Timeless · Negative · Everyday, not technical · Rated PG