bioprinted
Tissue-deposited by machine
Bioprinted describes biological material—typically tissue or organs—produced using 3D printing technology with living cells as the "ink." The process layers cells to build structures that mimic natural tissue: bioprinted skin grafts for burn victims, researchers developed bioprinted cartilage.
The technology aims toward printing functional organs for transplant, though that remains largely experimental.
Temporary elevated work structure
- hydrogelWater-swollen polymer structure
- cellularComposed of small units
- vascularizationFormation of blood vessels
- layeredHaving multiple levels
porous · living · engineered · construct · patch · graft · dermis · epidermis
In successive strata
- extrusionPushing through a die
- inkjetSpray-based printing method
- laser-assistedAided by focused light
- stereolithographyUV resin 3D printing
nozzle · deposition · digital · precision · resolution · fidelity · reproducible · scalable
Move tissue between bodies
- liverAbdominal detoxifying organ
- kidneyBlood-filtering organ
- heartCirculatory system's pump
- bladderOrgan holding urine
cornea · cartilage · bone · implantation · vascularized · functional · miniature · organoid
Facility for scientific investigation
- researchSystematic fact-finding effort
- prototypeFirst functional specimen
- proof-of-conceptFeasibility demonstration
- preclinicalBefore human trials
in-vitro · FDA · ethics · regulation · emerging · developmental · investigational · frontier
Adapted for an individual
- bespokeMade to individual specifications
- tailoredAdjusted to fit exactly
- made-to-orderCreated to individual specifications
- individualizedAdapted for one person
Gene-editing molecular machinery
- differentiationRecognizing meaningful differences
- proliferationRapid increase in quantity
- angiogenesisFormation of new vessels
- fibroblastsCollagen-producing connective tissue cells
osteoblasts · progenitor · autologous · biomimetic · restorative · therapeutic
scaffold
Temporary elevated work structure
- hydrogelWater-swollen polymer structure
- cellularComposed of small units
- vascularizationFormation of blood vessels
layered · porous · living · engineered · construct · patch · graft · dermis · epidermis · muscle
layer-by-layer
In successive strata
- extrusionPushing through a die
- inkjetSpray-based printing method
- laser-assistedAided by focused light
stereolithography · nozzle · deposition · digital · precision · resolution · fidelity · reproducible · scalable · automated
transplant
Move tissue between bodies
bladder · cornea · cartilage · bone · implantation · vascularized · functional · miniature · organoid · replacement
laboratory
Facility for scientific investigation
- researchSystematic fact-finding effort
- prototypeFirst functional specimen
- proof-of-conceptFeasibility demonstration
preclinical · in-vitro · FDA · ethics · regulation · emerging · developmental · investigational · frontier · pioneering
personalized
Adapted for an individual
- bespokeMade to individual specifications
- tailoredAdjusted to fit exactly
- made-to-orderCreated to individual specifications
individualized · custom-fit · unique · on-demand · point-of-care
CRISPR
Gene-editing molecular machinery
- differentiationRecognizing meaningful differences
- proliferationRapid increase in quantity
- angiogenesisFormation of new vessels
fibroblasts · osteoblasts · progenitor · autologous · biomimetic · restorative · therapeutic
bioprintedendogenous
Originating from within
natural · unengineered · native · wild-type · innate
bioprintedtraditional
Following long-held customs
unmanufactured · natural · conventional · unengineered · transplanted