signal peptide
Protein's address label
A signal peptide is a short sequence of amino acids at the beginning of a newly made protein that acts as an address label, directing the protein to its destination within or outside the cell.
Once the protein reaches the correct location—typically the endoplasmic reticulum—the signal peptide is usually clipped off and degraded.
Also called signal sequence or leader peptide.
- secretoryReleasing substances from cells
- endoplasmic reticulumCytoplasmic membrane network for synthesis
- cleavageTendency to split cleanly
- translocationMovement to another place
- ribosomeProtein synthesis site
membrane · targeting · secretory pathway · hydrophobic · protease · vesicle · export · sorting · chaperone · lumen · processing · precursor · secretion · zip code · trafficking · cleavable
- proteinsprotein, proteins, albumin, collagen, casein
- ER biologytubules, sheets, protein folding, N-glycan, HMG-CoA reductase
- Protein ExpressionE. coli, plasmid, vector, promoter, transfection
- bacterial secretion
- peptidespolypeptides, dipeptide, tripeptide, tripeptides, pentapeptide
- translationtranslator, literal translation, literary translation, free translation, French translation
signal, signals, signaled, signaling, signaller, signalman, signify, significant, significance