pore-forming

Making membrane holes

Pore-forming describes substances or processes that create small holes or channels, typically in cell membranes.

The term appears most often in biology and biochemistry: pore-forming toxins punch holes in target cells, disrupting their function.

Pore-forming proteins can serve defensive or pathogenic purposes, allowing molecules to pass through otherwise impermeable barriers.

mechanism

insertion

Placing something within

lysis · leakage · depolarization · osmotic · rupture · conformational · hydrophobic · assembly · multimerization · spanning

cellular

membrane

Thin tissue sheet

necrosis · cytotoxic · T-cell · macrophage · pathogen · complement

toxins

CDC

U.S. public health agency

pathogenic · virulence · secreted · exotoxin

research

electrophysiology

Biology's electrical activity science

nanopore · sequencing · biosensor · crystallography · mutagenesis · recombinant · purification · assay · fluorescence

Opposites
membrane integrity

pore-formingsealing

Making impermeable

impermeable · occluding · plugging · waterproofing · coating

structural action

pore-formingsealing

Making impermeable

plugging · occluding · filling · closing · blocking

Family

form, formation, forming, porous, pore, formative

Familiarity
Top 1,000,000
Profile
Used worldwide · Timeless · Rated G