drug discovery
Finding new medicines
Drug discovery is the process of identifying and developing new medications.
It encompasses finding compounds that might treat diseases, testing them for safety and effectiveness, and refining them into viable drugs.
The process typically spans years and involves screening thousands of candidates: The company invested heavily in drug discovery for rare cancers.
Most compounds fail before reaching patients.
Evaluative selection process
- assaysTests for composition
- preclinicalBefore human trials
- high-throughputRapid large-scale processing capacity
- in vitroIn an artificial environment
in vivo · biomarkers · toxicology · pharmacokinetics · molecule · optimization · ligand · receptor
Algorithms that improve from data
- artificial intelligenceMachines mimicking human thought
- genomicsStudy of entire genetic sequences
- bioinformaticsComputational analysis of genetic data
- CRISPRGene-editing molecular machinery
Controlled health research experiments
- FDA approvalOfficial drug safety certification
- NDASecrecy contract, abbreviated
- regulatoryInvolving official oversight
- candidate selectionChoosing among job seekers
proof-of-concept · attrition · milestone · commercialization · fast track
Treatment using pharmaceutical agents
- treatmentCare for an ailment
- chemotherapyAnti-cancer drug treatment
- antibioticsBacteria-destroying medicines
- antiviralsMedicines that inhibit viruses
immunotherapy · biologics · monoclonal antibodies · gene therapy · targeted therapy · efficacy · indication · best-in-class
Legal rights over inventions
- exclusive rightsProtected singular ownership claims
- inventionNew device or method
- patent applicationFormal invention protection request
- USPTOFederal intellectual property agency
EPO · claims · prior art · non-obviousness · novelty · patentability · license · infringement
screening
Evaluative selection process
- assaysTests for composition
- preclinicalBefore human trials
- high-throughputRapid large-scale processing capacity
in vitro · in vivo · biomarkers · toxicology · pharmacokinetics · molecule · optimization · ligand · receptor · enzyme
machine learning
Algorithms that improve from data
- artificial intelligenceMachines mimicking human thought
- genomicsStudy of entire genetic sequences
- bioinformaticsComputational analysis of genetic data
clinical trials
Controlled health research experiments
- FDA approvalOfficial drug safety certification
- NDASecrecy contract, abbreviated
- regulatoryInvolving official oversight
candidate selection · proof-of-concept · attrition · milestone · commercialization · fast track
pharmacotherapy
Treatment using pharmaceutical agents
- treatmentCare for an ailment
- chemotherapyAnti-cancer drug treatment
- antibioticsBacteria-destroying medicines
antivirals · immunotherapy · biologics · monoclonal antibodies · gene therapy · targeted therapy · efficacy · indication · best-in-class · biosimilars
intellectual property
Legal rights over inventions
- exclusive rightsProtected singular ownership claims
- inventionNew device or method
- patent applicationFormal invention protection request
USPTO · EPO · claims · prior art · non-obviousness · novelty · patentability · license · infringement · exclusivity
drug discoverysurgical intervention
Invasive medical procedure
psychotherapy · physical therapy · lifestyle modification · watchful waiting · palliative care
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