scrapie
Fatal ovine encephalopathy
Scrapie is a fatal degenerative disease affecting the nervous systems of sheep and goats.
Infected animals scrape against fences and other objects, hence the name.
The disease belongs to a class of conditions caused by prions—misfolded proteins that trigger progressive brain damage.
Scrapie was the first recognized transmissible spongiform encephalopathy, related to mad cow disease in cattle and Creutzfeldt-Jakob disease in humans.
Containing or resembling proteins
- amyloidCross-beta protein aggregate
- aggregationCombined collection of items
- kuruPrion disease from cannibalism
- conformationalRelating to spatial arrangement
protein · pathogenic · molecular · transmissible · spongiform · encephalopathy · plaque · neurodegenerative
Development before emergence
- infectiousAble to spread disease
- transmissibleAble to spread between individuals
- spongiformResembling a sponge's structure
- encephalopathyDisease impairing brain function
diagnosis · quarantine · veterinary · neuropathology · degeneration · biosecurity · epidemiology · pathogenesis
Impaired voluntary movement control
- tremorsSlight shaking movements
- itchingIrritating skin sensation
- scratchingRaking with nails
- rubbingApplying pressure while moving
neurodegeneration · dementia · myoclonus · wasting · behavioral · gait · incoordination · lip-smacking
proteinaceous
Containing or resembling proteins
- amyloidCross-beta protein aggregate
- aggregationCombined collection of items
- kuruPrion disease from cannibalism
conformational · protein · pathogenic · molecular · transmissible · spongiform · encephalopathy · plaque · neurodegenerative · variant
incubation
Development before emergence
- infectiousAble to spread disease
- transmissibleAble to spread between individuals
- spongiformResembling a sponge's structure
encephalopathy · diagnosis · quarantine · veterinary · neuropathology · degeneration · biosecurity · epidemiology · pathogenesis · fatal
ataxia
Impaired voluntary movement control
- tremorsSlight shaking movements
- itchingIrritating skin sensation
- scratchingRaking with nails
rubbing · neurodegeneration · dementia · myoclonus · wasting · behavioral · gait · incoordination · lip-smacking · emaciation
flock
Animals gathered together
wool · lamb · pasture · grazing · livestock · merino · shepherd · herding · lambing · fleece
scrapiebacterial infection
Illness from harmful microorganisms
viral infection · viral disease · influenza · anthrax · foot-and-mouth disease
- scrape bySurvive with minimal resources
- scrape togetherAssemble with effort
- scrape offRemove by rubbing hard
- scrape upGather with effort
- scrape the bottom of the barrelUse last, worst resources
- scrape throughBarely manage success