peptidyl transferase
Ribosomal catalytic center
Peptidyl transferase is the enzymatic activity that forms peptide bonds during protein synthesis.
Located in the large ribosomal subunit, it catalyzes the transfer of the growing amino acid chain from one transfer RNA molecule to the next, linking amino acids together.
The activity resides in ribosomal RNA rather than protein—a rare example of RNA acting as a catalyst.
Base triplet encoding amino
- anticodontRNA's matching triplet
- mRNAGene's working copy
- tRNAAmino acid transporter molecule
- reading frameTriplet-grouping starting point
initiation · termination · genetic code · wobble · fidelity · erythromycin
Bass increase from nearness
- active siteEnzyme region binding substrates
- activation energyMinimum energy for transformation
Polypeptide's starting residue
- C-terminusProtein chain's ending point
- residueMatter left behind
- carbonylC=O functional group
- covalent bondShared-electron atomic link
codon
Base triplet encoding amino
reading frame · initiation · termination · genetic code · wobble · fidelity · erythromycin
proximity effect
Bass increase from nearness
- active siteEnzyme region binding substrates
- activation energyMinimum energy for transformation
translocation
Movement to another place
N-terminus
Polypeptide's starting residue
- C-terminusProtein chain's ending point
- residueMatter left behind
- carbonylC=O functional group
peptidyl transferasepeptidase
Bond-cleaving enzyme
protease · proteinase · trypsin · pepsin
transfer, pepsin, peptide, transferal, polypeptide, peptides, polypeptides, protein synthesis, tripeptide