megacolon

Abnormally widened intestine

Megacolon is abnormal dilation of the colon, either congenital or acquired.

Hirschsprung's disease causes congenital megacolon through absence of nerve cells in the bowel wall.

Acquired forms result from chronic constipation, obstruction, or conditions like Chagas disease.

The enlarged colon loses its ability to move waste normally, causing severe constipation and abdominal distension.

anatomical

large intestine

Lower digestive tract portion

rectum · sigmoid · cecum · lumen · diameter · intestinal · visceral · abdominal · gastrointestinal · perforation

symptoms

constipation

Difficult, infrequent waste elimination

cramps · tenderness · nausea · vomiting · failure to thrive · tympany · anorexia · malaise

congenital

ganglion

Peripheral nerve cell cluster

manometry · transition zone · pull-through · anorectal · neuropathy · enteric · congenital · anomaly

treatment

resection

Surgical tissue removal

laxatives · surgery · anastomosis · ileostomy · hospitalization · nasogastric · supportive care · antibiotics · monitoring

acquired

toxic

Capable of causing harm

diabetic · psychogenic · chronic constipation · infectious

Opposites
colonic motility/function

megacolonirritable bowel syndrome

Functional gastrointestinal disorder

Family

mega, colon, megabyte, colicky, colitis, colonoscopy, colonic, colectomy, colorectal

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