demyelinated
Nerve coating lost
Demyelinated describes nerve fibers that have lost their myelin sheath, the protective fatty coating that insulates nerves and allows electrical signals to travel efficiently.
When nerves become demyelinated, signals slow down or fail to transmit properly, causing neurological symptoms.
The condition is central to diseases like multiple sclerosis: MRI revealed several demyelinated lesions in her brain.
The related noun is demyelination.
Autoimmune demyelinating neurological disease
- lesionsAreas of damaged tissue
- plaquesCommemorative mounted inscriptions
- white matterPale neural fiber tissue
- axonsNeuron output extensions
nerve damage · MRI · brain · spinal cord · neurodegeneration · inflammation · autoimmune · Guillain-Barré
Of nerve cell extensions
- nerve fiberSignal-conducting neural extension
- insulationThermal transfer prevention
- saltatory conductionImpulse jumping between myelin gaps
- nodes of RanvierGaps in nerve insulation
macrophages · T-cells · antibodies · complement · microglia · astrocytes · blood-brain barrier · cytokines
Loss of sensation
- tinglingSlight stinging sensation
- weaknessDeficiency in force
- fatigueWeariness from prolonged exertion
- vision lossDiminished ability to see
paralysis · spasticity · tremor · ataxia · cognitive impairment · pain · vertigo · slurred speech
Immune response protein
- immunosuppressantsDrugs reducing body defenses
- steroidsPerformance-enhancing hormones
- rehabilitationRecovery from injury/addiction
- physical therapyRehabilitative movement-based medical care
disease-modifying · neurologist · infusion · relapse prevention · neuroprotection · clinical trial
multiple sclerosis
Autoimmune demyelinating neurological disease
- lesionsAreas of damaged tissue
- plaquesCommemorative mounted inscriptions
- white matterPale neural fiber tissue
axons · nerve damage · MRI · brain · spinal cord · neurodegeneration · inflammation · autoimmune · Guillain-Barré · central nervous system
axonal
Of nerve cell extensions
- nerve fiberSignal-conducting neural extension
- insulationThermal transfer prevention
- saltatory conductionImpulse jumping between myelin gaps
nodes of Ranvier · macrophages · T-cells · antibodies · complement · microglia · astrocytes · blood-brain barrier · cytokines · repair
numbness
Loss of sensation
- tinglingSlight stinging sensation
- weaknessDeficiency in force
- fatigueWeariness from prolonged exertion
vision loss · paralysis · spasticity · tremor · ataxia · cognitive impairment · pain · vertigo · slurred speech · difficulty walking
interferon
Immune response protein
- immunosuppressantsDrugs reducing body defenses
- steroidsPerformance-enhancing hormones
- rehabilitationRecovery from injury/addiction
physical therapy · disease-modifying · neurologist · infusion · relapse prevention · neuroprotection · clinical trial
demyelinatedmyelinated
Having fatty nerve coating
intact · insulated · sheathed · healthy · ensheathed